The key is to not put all ones eggs in one basket. If you believe in the law of statistics, at some point if you try to apply for multiple opportunities, you will get a bite. It's when we place too much priority on one job or opportunity that we are most vulnerable. I truly believe the best opportunities arise when you least expect them. Keep applying for jobs...your ship will come in.
I once applied for a sales position at two different companies. In one week, I received a reply that I would be hired with the next opening...in about a month's time. The second job came from an interview I had with the president of the franchise on a Friday. I was in his office interviewing and he offered me a position. I remember he seemed very successful and had a portable golf putting set up. Well, by Monday, I heard that the first company who offered me a position decided to hire two other people. And, the president who offered me a firm position was fired over the weekend. That was two jobs I thought were "gos" that became "misses." The great lesson in this is that the next week my boss ended up leaving the company, and I was offered her job, which was much more suited for me. So, life and these opps a work in mysterious ways.